If you trust Twitter so much to find needed information after Google, Yahoo and other SE, you might want to know this information about search information in Twitter for specific area, with TweepSearch you can search information directly from Twitter user bio to be more specific for example if searching for designer you will find ones

Here is the screenshot of TweepSearch Search Engine

TweepSearch

First thing first, search for the profile for example @missy and afterward search for the keyword that related to your query so the result will be more relevant